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Product Sheet
Active Ingredient(s)
Metformin, Glyburide
Reference Brand
Glucovance
Product Origin
Generic Product
Reference Manufacturer
Sanofi
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Diabetes Management
Product Category
Antidiabetic
Pharmacological Class
Biguanide, Sulfonylurea
Clinical Indications
Type 2 Diabetes mellitus
Manufacturer Description
This combination is indicated to manage blood glucose levels in patients, designed to support insulin sensitivity and alleviate glycemic imbalances in type 2 diabetes.
Mechanism of Action
Metformin decreases glucose production in the liver, while glyburide stimulates the pancreas to release more insulin, together helping to regulate and stabilize blood sugar levels.
Route of Administration
Oral
Onset Time
1 to 2 hours
Duration
12 to 24 hours
Contraindications
Diabetic ketoacidosis, Severe renal impairment
Severe Adverse Events
Lactic acidosis
Common Side Effects
Nausea, Abdominal discomfort
Uncommon Side Effects
Hypoglycemia, Metallic taste
Drug Interactions
Alcohol, Cimetidine
Pregnancy Safety Warnings
Consult a doctor; insulin is generally preferred.
Age Restrictions
Not recommended for children.
Storage Guidelines
Store at controlled room temperature.
Related Products
Metformin + Glipizide
Information associated with Metformin with Glyburide is curated and periodically reviewed using established medical references and prescribing guidelines. Content is intended for general awareness and should be verified with a licensed healthcare professional before use.
