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Product Sheet
Active Ingredient(s)
Azilsartan, Chlorthalidone
Reference Brand
Edarbyclor
Product Origin
Generic Product
Reference Manufacturer
Takeda
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Heart & Blood Pressure
Product Category
Angiotensin II Receptor Blocker, Diuretic
Pharmacological Class
ARB, Thiazide-like diuretic
Clinical Indications
Hypertension
Manufacturer Description
Indicated to help manage high blood pressure through dual actions that address both systemic resistance and fluid retention.
Mechanism of Action
Azilsartan blocks the binding of angiotensin II to its receptor, causing relaxation of smooth muscle. Chlorthalidone acts as a diuretic, enhancing sodium excretion, which reduces blood volume and blood pressure.
Route of Administration
Oral
Onset Time
1–2 hours
Duration
24 hours
Contraindications
Anuria
Severe Adverse Events
Renal impairment
Common Side Effects
Dizziness, Fatigue
Uncommon Side Effects
Hypotension, Electrolyte imbalance
Drug Interactions
Lithium, NSAIDs
Pregnancy Safety Warnings
Contraindicated in pregnancy.
Age Restrictions
Adults.
Storage Guidelines
Store in dry, cool conditions.
Related Products
Losartan, Hydrochlorothiazide
Information associated with Azilsartan with Chlorthalidone is curated and periodically reviewed using established medical references and prescribing guidelines. Content is intended for general awareness and should be verified with a licensed healthcare professional before use.
